Twins southpaw Francisco Liriano has held opposing left-handed hitters to a .228 average and .647 OPS, compared to marks of .252 and .731. As such, the Red Sox will feature a couple of notable right-handed hitters in Tuesday's lineup against Liriano.

Darnell McDonald will be in right field in place of Josh Reddick, while Jed Lowrie will start at shortstop for the first time since landing on the disabled list in mid-June. Lowrie is hitting .380 with a 1.012 OPS against lefties this year.

Tom Verducci from Sports Illustrated and the Major League Baseball Network joined Dennis & Callahan to talk about his cover story on Dustin Pedroia in this week's SI. Pedroia -- who had two hits and two runs in Monday's win over the Twins -- is perhaps having the best season of his career, batting .311 with an on-base percentage of .411 and OPS of .880.

When Adrian Gonzalez arrived in Boston, he was hailed as the next great Red Sox slugger.

It has been almost nine years since the Twins let David Ortiz go, and the Red Sox designated hitter has given his former club reason to regret its decision ever since. On Monday, that regret was direct, as Ortiz smashed a two-run homer in the sixth and then, with the game tied 6-6 in the top of the ninth, he rifled a go-ahead single to center in an eventual 8-6 victory for the Sox in Minnesota.

Terry Francona told the media on Monday that Bobby Jenks -- who was scheduled to throw a side session on Sunday and then go to Fort Myers to pitch in simulated games -- was hospitalized over the weekend with intestinal turmoil and will undergo a colonoscopy Monday.

Jenks has been on the disabled list three times this season and has not pitched since July 7 as he continues to battle a back injury. He has a 2-2 record with a 6.32 ERA in 19 appearances this season.

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Outfielder Ryan Kalish and pitcher Junichi Tazawa have joined the Pawtucket Red Sox.

Kalish played just 14 games with Pawtucket this season before injuring his left shoulder on April 21. He rejoined Pawtucket after completing his two-game rehabilitation stint with Single-A Lowell.

According to a report from Troy Renck of the Denver Post, the Rockies have signed Kevin Millwood.

Millwood, who was released by the Red Sox on Sunday, could start for Colorado on Wednesday, according to the Renck report. He signed a minor-league deal with the Sox in May and made 13 starts with Triple-A Pawtucket, posting a 5-1 record and 4.28 ERA. Millwood last pitched for Pawtucket Friday night, allowing four runs on eight hits over six innings against Buffalo.

With shortstop Jed Lowrie activated to the Red Sox roster, left-hander Randy Williams has been optioned to Triple-A Pawtucket. Williams appeared in seven games after being called up from Pawtucket on July 16, forging a 6.48 ERA while walking five and striking out six in 8 1/3 innings. Left-handers were 4-for-16 against the 35-year-old.

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The Red Sox open a three-game series vs. the Twins at Target Field on Monday night, with Tim Wakefield (6-4, 4.99) ERA once again looking for career win No. 200. This will be the third attempt at a 200th victory for Wakefield, who will be opposed by Scott Baker (8-6, 3.01). 

After missing nearly two months with a shoulder injury, Jed Lowrie was activated on Monday. He will get the start at third base as Kevin Youkilis receives a day off for rest. Lowrie was 7-of-17 with four doubles and two walks during a five-game rehab stint in Triple-A Pawtucket.

It has been the most deliberate season for draft pick signings ever.